Case Study Graves Disease
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Case discussion-Graves disease
Nonetheless, we believe that the current treatment approaches have a lack of specificity and can have undesired consequences e. There is thus a need for concerted efforts that warrant further investments. Autoimmunity in human primary immunodeficiency diseases. What is the best definitive treatment for Graves' disease? A systematic review of the existing literature. Ann Surg Oncol. PubMed Article Google Scholar. Autoimmune thyroid disorders. Autoimmun Rev. Brent GA. Clinical practice. Graves' disease. N Engl J Med. Orgiazzi J. Thyroid autoimmunity.
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Cancer epigenetics reaches mainstream oncology. Nat Med. Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Selenium and the course of mild Graves' orbitopathy. Selenium supplementation for patients with Graves' hyperthyroidism the GRASS trial : study protocol for a randomized controlled trial. Duntas LH. The role of iodine and selenium in autoimmune thyroiditis. Horm Metab Res. Goodnow CC. Pathways for self-tolerance and the treatment of autoimmune diseases. Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells. J Immunol. DeGroot LJ. Effects of irradiation on the thyroid gland.
Endocrinol Metab Clin North Am. Radiation therapy for Hodgkin's disease followed by hypothyroidism and then Graves' hyperthyroidism. Clin Nucl Med. Measures of thyroid function among Belarusian children and adolescents exposed to iodine from the accident at the Chernobyl nuclear plant. Environ Health Perspect. Weetman A. Immune reconstitution syndrome and the thyroid. A potential role for interleukin-7 in T-cell homeostasis.
Perspectives of the relationship between IL-7 and autoimmune diseases. Clin Rheumatol. The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. Shenkman L, Bottone EJ. Antibodies to Yersinia enterocolitica in thyroid disease. Ann Intern Med. Yersinia enterocolitica infection and thyroid disorders. Yersinia enterocolitica infection and thyroid diseases. Acta Endocrinol Copenh. CAS Google Scholar. Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease.
The clinical and physiological spectrum of interferon-alpha induced thyroiditis: toward a new classification. Thyroid autoimmunity and dysfunction associated with type I interferon therapy. Clin Exp Med. Martocchia A, Falaschi P. Amino acid sequence homologies between HCV polyprotein and thyroid antigens. Intern Emerg Med. Crow YJ, Manel N. Aicardi-Goutieres syndrome and the type I interferonopathies. Nat Rev Immunol. Exploring autoimmunity in a cohort of children with genetically confirmed Aicardi-Goutieres syndrome.
Peculiarities of autoimmune thyroid diseases in children with Turner or Down syndrome: an overview. Ital J Pediatr. Peculiarities of Graves' disease in children and adolescents with Down's syndrome. Trisomy 21 consistently activates the interferon response. The genetic basis of graves' disease. Curr Genomics. Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of multiplex families.
Am J Hum Genet. Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease. Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective. J Biol Chem. A novel pathogenic peptide of thyroglobulin induces autoreactive T-cell and B-cell responses in both high and low responder mouse strains. CD3G gene defects in familial autoimmune thyroiditis. Scand J Immunol. Role of genetic and non-genetic factors in the etiology of Graves' disease. J Endocrinol Invest. AIRE genetic variants and predisposition to polygenic autoimmune disease: The case of Graves' disease and a systematic literature review.
Hum Immunol. Defective function of Fas in T cells from paediatric patients with autoimmune thyroid diseases. Differential expression of Fas system apoptotic molecules in peripheral lymphocytes from patients with Graves' disease and Hashimoto's thyroiditis. Regulation of apoptosis in endocrine autoimmunity: insights from Hashimoto's thyroiditis and Graves' disease.
Ann N Y Acad Sci. PubMed Google Scholar. Down syndrome, autoimmunity and T regulatory cells. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL expression from CD4 lymphocytes. J Allergy Clin Immunol. Zarour HM. Reversing T-cell dysfunction and exhaustion in cancer. Clin Cancer Res. Endocrine side effects induced by immune checkpoint inhibitors.
Serological aggravation of autoimmune thyroid disease in two cases receiving nivolumab. J Dermatol. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. How apoptotic cells aid in the removal of their own cold dead bodies. Cell Death Differ. Marked variability in clinical presentation and outcome of patients with C1q immunodeficiency. Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Autoantibodies against complement C1q correlate with the thyroid function in patients with autoimmune thyroid disease. The expression of microvesicles in the blood of patients with Graves' disease and its relationship to treatment. Grave's disease Horm Res. Kristensen B.
Regulatory B and T cell responses in patients with autoimmune thyroid disease and healthy controls. Dan Med J. Frequency and characteristics of TBII-seronegative patients in a population with untreated Graves' hyperthyroidism: a prospective study. Autoantibodies to the thyrotropin receptor. Endocr Rev. IP in autoimmune thyroiditis. Etiopathogenesis of Basedow's disease. Trends and current aspects. Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity. McLachlan SM. Stassi G, de Maria R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Expression of osteopontin in patients with thyroid dysfunction. PLoS One. The expression and pathophysiological role of osteopontin in Graves' disease.
The role of osteopontin in the induction of the CD40 ligand in Graves' disease. Chemokine C-C motif ligand 20, a potential biomarker for Graves' disease, is regulated by osteopontin. Increased chemokine C-C motif ligand 21 expression and its correlation with osteopontin in Graves' disease. IgA deficiency and autoimmunity. Nat Genet. Immunology of IgG4-related disease. Elevated serum immunoglobulin G4 levels in patients with Graves' disease and their clinical implications.
Brief Report: spuriously low serum IgG4 concentrations caused by the prozone phenomenon in patients with IgG4-related disease. Arthritis Rheumatol. Graves' disease patients with persistent hyperthyroidism and diffuse lymphoplasmacytic infiltration in the thyroid show no histopathological compatibility with IgG4-related disease. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population.
Treatment of autoimmune hyperthyroidism in a murine model of Graves' disease with tumor necrosis factor-family ligand inhibitors suggests a key role for B cell activating factor in disease pathology. BLyS and April serum levels in patients with autoimmune thyroid diseases. Serum BAFF concentrations in patients with Graves' disease and orbitopathy before and after immunosuppressive therapy. A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency. Qamar N, Fuleihan RL. The hyper IgM syndromes. Clin Rev Allergy Immunol. Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naive-to-memory B-cell transition.
Nat Commun. Wood A, Shilatifard A. Posttranslational modifications of histones by methylation. Adv Protein Chem. Genetic-epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunity. Savino W. The thymus is a common target organ in infectious diseases. PLoS Pathog. Gupta B, Hawkins RD. Epigenomics of autoimmune diseases. Immunol Cell Biol. Epigenetic alterations underlying autoimmune diseases. Shahbazian MD, Grunstein M. Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem. Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease. Mol Cell Endocrinol.
Thyroid epigenetics: X chromosome inactivation in patients with autoimmune thyroid disease. Epigenetics changes associated to environmental triggers in autoimmunity. Genome-wide DNA methylation analysis in Graves' disease. Can we predict relapse in Graves' disease? Results from a systematic review and meta-analysis. Diagnosis and treatment of Graves' disease. Google Scholar. Cooper DS. Antithyroid drugs. Antithyroid drug regimen for treating Graves' hyperthyroidism. Cochrane Database Syst Rev. Anti-cytokine autoantibodies in autoimmune diseases. Am J Clin Exp Immunol.
Does immunosuppressive therapy improve outcomes in Graves' disease? A systematic review and meta-analysis. Treatment modalities for Graves' ophthalmopathy: systematic review and metaanalysis. Ganesan A. Multitarget drugs: an epigenetic epiphany. Production, isolation, and characterization of rabbit anti-idiotypic antibodies directed against human antithyrotrophin receptor antibodies. J Clin Invest. Randomized trial of intravenous immunoglobulins versus prednisolone in Graves' ophthalmopathy. Intravenous immunoglobulin versus corticosteroid in treatment of Graves' ophthalmopathy.
Davies TF, Latif R. Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies. Expert Opin Ther Targets. Download references. Funders had no role in the design, analysis, or writing of this article. Describe the place where you live essay urban education essay finance study Case behavioral on essay about my favourite writer. Best essay intro ever funny literary device essay title. Sample essay for college scholarship application. Procrastination narrative essay research paper format free download. Ways to start of a essay What is the chapter 5 in research paper introduction in essay ielts. What is my leadership style essay, sat essay question and answer, example of a closing statement in an essay.
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